Set in a dystopian version of Italy, the series follows the Social Welfare Agency, a seemingly benign public corporation secretly operated by the Italian government’s intelligence division, Section 2. Under the cold, pragmatic leadership of civilian director Giuseppe and seasoned operative Jean, the Agency recruits young girls who have suffered horrific trauma, abuse, or near-death experiences. These broken children are subjected to intensive cybernetic augmentation, thorough physical conditioning, and intense chemical and psychological conditioning—known as "conditioning"—which erases their memories, enhances their physical capabilities, and instills absolute, unwavering loyalty to their adult handlers, known as "fratellos."The narrative centers primarily on Henrietta, a gentle girl paired with the distant and grief-stricken Jean, alongside other pairs like the energetic Rico and her handler Triela, the troubled Claes, and the fiercely independent Angelica. These augmented girls are deployed as lethal assassins and counter-terrorism operatives to eliminate the "Padania Republic Faction," a violent separatist terrorist organization responsible for widespread bloodshed.Initially, the operations appear straightforward, showcasing the girls' chilling efficiency and superhuman combat prowess. However, the emotional core of the series quickly complicates the cold violence. Despite the memory wipes and psychological conditioning, the girls retain fragments of their humanity and form deeply emotional, sometimes obsessive, bonds with their fratellos. Henrietta desperately seeks Jean’s validation and affection, often struggling against the mechanical coldness with which he treats her, while the other girls navigate similar dynamics of love, dependency, and protection.As the conflict with the Padania Republic intensifies, the tragic reality of the girls' existence becomes increasingly apparent. The
cybernetic enhancements and heavy conditioning come at a devastating cost: severe physical deterioration and a drastically shortened lifespan. The handlers grapple with their own moral culpability, knowing they are turning children into disposable weapons while simultaneously growing attached to them.The dramatic tension peaks during a brutal, large-scale confrontation with the terrorists, culminating in the tragic demise of several key operatives. Angelica, whose memory wipe had advanced to the point of total identity loss, suffers a heartbreaking final mission, while Henrietta and Jean face their inevitable, sorrowful fates together. The series concludes not with a triumphant victory, but as a poignant, haunting exploration of exploitation, loyalty, and the heartbreaking impossibility of retaining pure humanity in a world consumed by violence and
political corruption.