The narrative begins with the Gecko brothers, Seth and Richie, fleeing a bloody bank robbery in Texas toward the Mexican border, taking minister Jacob Fuller and his family hostage in their RV. Seth, pragmatic and cynical, wants a clean break, while Richie, tormented by disturbing psychic visions, is erratic and spiraling into madness. Unbeknownst to them, the brothers are unwittingly being hunted by the relentless Texas Ranger Earl McGraw and the stoic Agent Freddie Gonzalez, who seeks vengeance for the murder of his mentor.The dynamic shifts dramatically when the group reaches the designated rendezvous point: the Titty Twister, a remote strip club in the middle of the desert. Unknown to the humans, the establishment is actually a front for a centuries-old nest of Mesoamerican vampire-like creatures known as *culebras*. As night falls, the patrons and dancers reveal their true, predatory nature, locking the doors and trapping the desperate survivors inside.The ensuing night becomes a relentless, blood-soaked siege. Seth, Richie, and the Fullers are forced into an uneasy alliance to survive the onslaught. During the chaos, Richie falls under the spell of Santanico Pandemonium, the alluring and terrifying *culebra* queen. It is revealed that Richie is destined to be her consort, awakening an
ancient prophecy linked to his bizarre visions. Meanwhile, Jacob Fuller sacrifices himself to save his children, cementing the group's desperate resolve.By morning's light, the surviving humans—Seth, Kate, and Scott Fuller—along with Freddie Gonzalez, who changes sides after uncovering the corruption within his own department and the true nature of the *culebras*, manage to escape the ruins of the club. Seth and Santanico, now bonded, depart together, while Richie's transformation alters his humanity forever.Season two expands the mythology into the
criminal underworld of Mexico and Texas. Seth and a newly liberated Santanico try to forge a new life and syndicate, but they are pulled back into conflict when an ancient and powerful *culebra* known as Lord Amancio Malvado rises to power. Concurrently, Richie forms a volatile partnership with Carlos Madrugada, leading a heist crew and diving deeper into the dark magic of the *culebra* bloodlines. Freddie Gonzalez and a hardened Kate Fuller team up as *culebra* hunters, tracking the Gecko brothers across the cartel-infested landscape. Ultimately, the disparate factions must unite to face a catastrophic, apocalyptic threat: the awakening of a primordial *culebra* god, Xibalba, which threatens to consume both the criminal empires and the mortal world, culminating in a violent, high-stakes war that blurs the lines between monsters and men.