Set in the remote town of Fairlake, West Virginia, the story unfolds during the annual Mountain Man Festival on
Halloween night. The town is thrown into terror when a trio of infamous, inbred cannibals—Three Finger, Saw Tooth, and One Eye—are captured after a bloody massacre, accompanied by their patriarch, Maynard Odets, a deranged serial killer who has raised and guided them since childhood.Unbeknownst to the local authorities, the cannibals have a loyal and deeply disturbed college-age accomplice named Billy, who is dating Julian, a local law student. Billy’s ultimate motivation is to rescue his murderous mentors and execute a reign of terror, fueled by his twisted ideological alignment with their savage lifestyle. Meanwhile, a group of college students—Cruz, Lita, Billy, Julian, Gus, and Brittney—arrive in Fairlake for the festival, looking forward to a weekend of partying, costumes, and mind-altering substances.Unaware of the impending danger, the friends cross paths with Maynard and the mutants. As Halloween night descends, the town's small police force, led by Sheriff Angela Carter and Deputy Biggs, struggles to maintain order as Billy initiates his rescue plan. The cannibal trio, having broken free with Billy’s assistance, embarks on a brutal, systematic hunt through the town and the surrounding countryside.The college students soon find themselves separated and picked off one by one in gruesome, inventive fashion. Gus meets a violent end with a snowplow, while Brittney suffers a horrifying demise involving a barbed-wire trap. Cruz and Lita desperately try to survive as the net closes in. Sheriff Carter attempts to protect the town, but the sheer ferocity and cunning of the mutants, combined with Billy’s insider betrayal, quickly overwhelm the
police department. Deputy Biggs is brutally murdered, and Carter is left fighting a desperate losing battle.As the night reaches its bloody climax, Julian discovers Billy’s true allegiance and attempts to reason with him, only to be betrayed and left for dead. Cruz and Lita manage to fight back, temporarily stalling the mutants, but their escape is thwarted. In the end, Sheriff Carter is captured and subjected to a torturous fate. The movie concludes on a bleak note: despite the authorities' best efforts, the mutant clan—now including Billy as a fully inducted member—successfully escapes back into the deep West Virginia wilderness with their captives, ensuring that their horrific bloodline and reign of terror will continue unchecked.