Six years after the terrifying events in Kingston Falls, Billy Peltzer and his girlfriend Kate Beringer have relocated to New York City. They both work at the futuristic, high-tech corporate headquarters of the tyrannical billionaire Daniel Clamp. Billy is a mild-mannered draftsman, while Kate works as a tour guide. Meanwhile, their beloved, rules-abiding Mogwai, Gizmo, is captured by a ruthless genetic researcher named Dr. Catheter inside the Clamp Tower’s clandestine laboratory. Billy manages to infiltrate the lab and rescue Gizmo, but not before the creature accidentally gets splashed with water.This tragic misstep births a new batch of mischievous Mogwai, led by the cruel and ambitious Mohawk. Seeking dominance, Mohawk and his cronies terrorize the skyscraper, eventually finding a fast-food restaurant inside the building's massive atrium. Despite Billy and Kate's desperate warnings, the creatures consume food past midnight, transforming into vicious, scaly Gremlins. Chaos instantly erupts as the monsters sabotage the building's advanced security systems, take Clamp hostage, and begin a violent rampage through the upper floors, threatening to escape into the bustling streets of Manhattan and unleash a
global catastrophe.As the body count rises and the facility plunges into panic, Billy, Kate, and a frantic Clamp team up to stop the horde. They realize conventional weapons are useless against the multiplying menace. Desperate, Billy formulates a high-stakes plan utilizing the building's state-of-the-art sprinkler system and an experimental chemical compound stored in the basement labs.Meanwhile, the Gremlins mutate further after interacting with various scientific samples in Dr. Catheter's lab. A Brain Gremlin emerges as the articulate, intellectual leader of the pack, negotiating with Clamp and plotting to take over television networks to spread their anarchist gospel. A Spider-Gremlin captures Kate, intending to make her his bride, while Mohawk transforms into a terrifying, indestructible bat-like creature.Billy successfully lures the entire swarm of Gremlins into the building's central lobby just as Kate activates the overhead fire suppression system, dousing the monsters in gallons of electrified water. The ensuing chemical reaction causes the creatures to melt into bubbling puddles of slime. Mohawk tries to stop Billy, but Gizmo arrives heroically, armed with a makeshift bow and arrow tipped with a match, incinerating the bat-gremlin once and for all. With
the nightmare finally over, the surviving humans and Gizmo walk out into the New York night, safe at last from the chaotic terror.