Set in the
American Midwest during the mid-1980s, the narrative follows Maren Yearly, a young girl whose life is shattered when she succumbs to a visceral, lifelong compulsion: an insatiable urge to consume human flesh. Following a gruesome incident where she bites her babysitter, Maren’s overwhelmed father abandons her, leaving behind only a cassette tape of her life story, a birth certificate, and a small sum of cash. This abandonment sets Maren on a desperate cross-country odyssey to find her
estranged mother and understand the horrific nature of what she is.Along her lonely journey, Maren encounters other "eaters." Her first major encounter is with Sully, an older, unsettling drifter who possesses a strict code regarding his predatory impulses and senses Maren's raw innocence. Frightened by Sully’s intense, predatory fixation on her, Maren flees. Soon after, she meets Lee, a cynical, fiercely independent drifter who shares her affliction. Despite their guarded exteriors, an immediate, profound connection forms between the two outcasts. They decide to travel together, stealing cars and navigating the desolate margins of society, finding a rare sense of safety and acceptance in each other's troubled company.As they traverse the highways, their bond deepens into a tender romance, complicated by the constant, agonizing threat of discovery and the inescapable brutality of their shared hunger. Lee’s own deeply troubled backstory is revealed, showing a young man who fled an abusive, violent household after consuming his own cruel father. Maren and Lee experience moments of fleeting domestic normalcy, briefly settling into a shared home. However, the shadow of their nature always catches up to them.The story reaches a harrowing climax when Sully tracks Maren down, demanding she become his permanent companion. Consumed by a jealous obsession, Sully violently attacks them in their home, forcing a desperate, bloody struggle for survival. Lee is mortally wounded during the vicious confrontation, but not before he and Maren manage to overpower and kill their attacker. In Lee’s final moments, as he realizes he is dying from his severe injuries, he confesses his profound love to Maren. In an ultimate act of tragic devotion and acceptance, Maren consumes Lee entirely—a manifestation of their condition known as "bones and all"—absorbing him into her physically so that they will never truly be parted. The narrative closes with a profoundly changed Maren continuing her solitary journey, carrying the lingering memory of the only person who truly understood her.